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Onco Genomics

Onco genomics is a specialized diagnostic service offered at GeneAura to individuals and families with a personal or family history of cancer. Our experienced genetic counselors provide personalized guidance and support to help individuals understand their genetic risk of cancer, make informed decisions about genetic testing, and develop personalized strategies for cancer prevention and early detection.

Cancer is a significant public health concern in India, with a rising burden of cancer cases reported each year. According to the Indian Council of Medical Research (ICMR), cancer is the second leading cause of death in India, with an estimated 1.16 million new cancer cases diagnosed annually. The most common cancers in India include breast cancer, cervical cancer, oral cancer, and lung cancer, among others.

Risk for Men and Women:

Both men and women are at risk of developing cancer, although the types of cancer and the risk factors may vary between genders. In India, men are more likely to develop cancers such as oral cancer, lung cancer, and stomach cancer, while women are at higher risk of breast cancer, cervical cancer, and ovarian cancer. However, it's important to note that anyone can develop cancer, regardless of gender.

Hereditary Cancers:

Hereditary cancers are caused by inherited genetic mutations that increase the risk of developing certain types of cancer. These mutations can be passed down from one generation to the next and may significantly increase an individual's risk of developing cancer at a younger age than typically expected. Examples of hereditary cancer syndromes include:

Hereditary Breast and Ovarian Cancer Syndrome

Lynch syndrome (hereditary nonpolyposis colorectal cancer)

Li-Fraumeni syndrome

Hereditary diffuse gastric cancer syndrome

Familial adenomatous polyposis (FAP)

Importance of Cancer Genetic Screening:

Cancer geneticscreening plays a crucial role in helping individuals and families understand their genetic risk of cancer and make informed decisions about their health. Genetic counseling can provide valuable insights into inherited genetic factors that may increase the risk of certain cancers, allowing individuals to take proactive steps towards cancer prevention, early detection, and personalized cancer management strategies.

➔ Personal or family history of genetic disorders or birth defects

➔ Previous pregnancy with a chromosomal abnormality or genetic condition

➔ Abnormal ultrasound findings or other fetal abnormalities detected during pregnancy

➔ Exposure to environmental or teratogenic factors that may increase the risk of birth defects

➔ Concerns about genetic screening or testing options and their implications for your pregnancy and family.

Indications for Genetic Counseling:

You may benefit from cancer genetic counseling if you have any of the following indications:

➔ Personal or family history of cancer, especially at a young age

➔ Multiple relatives with the same or related types of cancer

➔ Rare or unusual cancers in the family

➔ Presence of certain hereditary cancer syndromes or genetic mutations

➔ Concerns about genetic risk factors for cancer and their implications for your health and family members

Our genetic counselors will work with you to assess your individual risk factors and provide personalized recommendations for prenatal screening and testing based on your specific needs and circumstances.

Non-Invasive Prenatal Testing (NIPT)

A simple blood test that analyzes cell-free fetal DNA in the mother's bloodstream to screen for
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First-Trimester Combined Screening

A combination of maternal blood tests and ultrasound measurements performed between
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Integrated Screening

A combination of maternal blood tests and ultrasound measurements performed between
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Diagnostic Testing

Invasive procedures such as chorionic villus sampling (CVS) and amniocentesis, which can
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The following prenatal screening tests are typically recommended during pregnancy:

First-Trimester Combined Screening: Between 11 and 14 weeks of pregnancy.

Non-Invasive Prenatal Testing (NIPT): Anytime after 10 weeks of pregnancy.

Second-Trimester Maternal Serum Screening: Between 15 and 20 weeks of pregnancy.

Fetal Anatomy Ultrasound: Between 18 and 22 weeks of pregnancy to assess fetal development and detect structural abnormalities.

Additional Diagnostic Testing (if indicated): Chorionic villus sampling (CVS) between 10 and 13 weeks of pregnancy or amniocentesis between 15 and 20 weeks of pregnancy.

At GeneAura, our dedicated team of genetic counselors provide you with the information, support, and guidance you need to make informed decisions about your pregnancy and genetic health.

We understand that navigating pregnancy can be overwhelming, and we are committed to supporting you every step of the way. Contact us today to schedule a genetic counseling appointment and take proactive steps towards a healthy and informed pregnancy.